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Porokeratosis

Porokeratosis is a rare skin disorder affecting fewer than 200,000 Americans. It typically presents as small, round patches on your skin that have a thin, raised border Porokeratosis is a skin condition which appears as raised brown bumps that may expand into scaly patches. They often have raised rings around the spots. Porokeratosis is not contagious, but it may.. Porokeratosis is a specific disorder of keratinization that is characterized histologically by the presence of a cornoid lamella, a thin column of closely stacked, parakeratotic cells extending through the stratum corneum with a thin or absent granular layer Porokeratosis is a skin condition involving lesions with thin center surrounded by raised ridges. It may be caused by genetics, UV rays or immunosuppression. Some lesions can develop into malignant carcinomas

Porokeratosis is the general term for a group of skin conditions causing small, discolored bumps with a raised border to appear on the skin. There is currently no cure for porokeratosis, but. A porokeratosis is a skin lesion characterized by thinned centre and surrounded by cornoid lamella (ridge-like border) caused by increasing number of ketatinocytes (skin cell surface). One of the common types of porokeratosis is Porokeratosis of Mibelli. (1 What is porokeratosis? Porokeratosis is a type of abnormal keratinisation. It presents as a reddish patch (either scaly or atrophic) with a well-defined ridge-like border [1]. Porokeratosis of Mibelli is the second most common form of porokeratosis [2]. Who gets porokeratosis of Mibelli

What is Porokeratosis? Porokeratosis is a medical condition in which the process of keratinization is affected and disrupted. The patient presents patches of atrophy on the skin, these having distinctive clinical and histopathological features. The most distinctive feature is the border surrounding the patch, this being obviously hyperkeratotic Die Porokeratose oder Porokeratosis ist eine chronische Verhornungsstörung der Haut. Einige von dieser Hauterkrankung Betroffene stellen bereits im Kindesalter schuppige Hautveränderungen besonders an den Beinen fest, die später knotig werden Although there are potentially many origins of this type of lesion including warts and intractable plantar keratoma, a very common cause of this type of growth is known as a porokeratosis. Porokeratosis is a general term to a group of dermatological problems that occur in various parts of the body. This discussion is limited to punctate porokeratosis

Porokeratosis. Porokeratosis is an uncommon dermatologic disorder. It is a disorder of keratinization that presents with keratotic papules or annular plaques with an elevated border. It has a distinct histologic hallmark of cornoid lamella, which is a column of tightly fitted parakeratotic cells in the upper epide Porokeratosis is a rare, acquired or inherited disorder of keratinization characterized by one or more atrophic macules or patches, each surrounded by a distinctive hyperkeratotic, ridge-like border called cornoid lamella ( picture 1D) [ 1,2 ]. Multiple clinical variants of porokeratosis exist Porokeratosis is a rare skin disorder characterized by skin lesions with a thin center surrounded by a distinctive ridge-like border. Risk factors include genetic inheritance, exposure to ultraviolet light, and immunosuppression. Five main types differ in appearance, location, and age of onset

Porokeratosis: Causes, Treatment, and Mor

Porokeratosis (PK) is an uncommon disorder of epidermal keratinization characterized by the appearance of one or more atrophic patches surrounded by a unique ridge-like border, histologically termed a cornoid lamella (1) Linear Porokeratosis. Characteristic findings on physical examination. This is one of the more rare variants. These lesions appear as classic porokeratosis; however, they follow the lines of Blaschko. Lesions are most commonly found on the extremities (distal > proximal) (Figure 3). They can occur on the trunk, often in a zosteriform distribution Porokeratosis is an uncommon cutaneous condition with multiple clinical variants that is defined by round patches with a raised, fine scaling border. Punctate porokeratosis is a rare variant of porokeratosis that is characterized by elevated, seed-like lesions of the palms and soles. While variants Porokeratosis is a group of uncommon skin conditions in which there is abnormal keratinization 1). The name porokeratosis means scaly pore, and is a misnomer as porokeratosis is not related to pores. Porokeratosis is a disorder of keratinization that presents with keratotic papules or annular plaques with a well-defined ridge-like border 2) Porokeratosis is a rare skin disorder characterized by one or more annular plaques with a surrounding raised horny border that spreads centrifugally. Variants of porokeratosis have been described that differ in morphologic shapes, distribution, and clinical course (Schamroth et al., 1997). However, as noted by Sybert (2010), several families with expression of more than one variant of.

Porokeratosis: What Is It And How Does It Impact My Health

  1. Porokeratosis is a rare skin disorder characterized by one or more annular plaques with a surrounding raised horny border that spreads centrifugally. Variants of porokeratosis have been described that differ in morphologic shapes, distribution, and clinical course (Schamroth et al., 1997). However, as noted by Sybert (2010), several families.
  2. Porokeratosis can appear as a single lesion or multiple lesions over any part of the foot on the plantar or bottom of the foot. People describe the discomfort as if there were several pebbles stuck to the bottom of their foot or in their shoe. Porokeratosis can become very painful over time depending on the location
  3. ated superficial actinic porokeratosis . DSAP is a skin condition with multiple, dry, scaly rings, each measuring up to 1 cm (1/2 inch) across. They are found mainly on the forearms and legs, in sun-exposed sites. It is sometimes confused with actinic keratosis which is also caused by sun exposure.

Porokeratosis - Wikipedi

Disseminated superficial actinic porokeratosis (DSAP) is a skin condition that causes dry, scaly patches. Symptoms include a large number of small, brownish patches with a distinctive border, found most commonly on sun-exposed areas of the skin (particularly the lower arms and legs) 3. Porokeratosis plantaris, palmaris et disseminata (PPPD) 4. Lineaire porokeratose (LP) 5. Punctate porokeratose (PP) Deze vijf varianten hebben als gezamenlijke kenmerk de aanwezigheid van een zogenaamde cornoïd lamel (= soort stukje abnormaal verhoornde huid) die uitsluitend onder de microscoop kan worden herkend Porokeratosis. In porokeratosis, the cornoid lamella, known as the histopathologic hallmark of porokeratosis, is revealed by dermoscopic examination as a well-defined, white-yellowish peripheral annular structure (white track, ''the outlines of a volcanic crater as observed from a high point '').. In disseminated superficial actinic porokeratosis, the peripheral track may be. Porokeratosis: Introduction Benign epidermal proliferation Distinct clinical & histologic features 5 clinical subtypes Erroneously name This is a porokeratosis or what we know as a porokeratosis. If it were in a weightbearing location, podiatrists would call it an intractable porokeratosis (IPK). The long held thought that a porokeratosis was a plugged sweat gland has been disproved by multiple scientific methods, including electron microscopy and histologic examination under.

Porokeratosis - Online Dermatology - First Der

Its worth getting looked at by your podiatrist. One of the most common, and easily treatable complaints that people come into my office for are small lesions called porokeratoses. Generally, the complaints patients present with are feeling like they are walking on a painful stone or thorn on the ball or heel of their foot, they don't recall. DSAP (short for Disseminated Superficial Actinic Porokeratosis) is a very rare skin disease with no known cure. Most dermatologists have not even heard about it leaving those with the condition to figure it out on their own. The DSAP Institute's mission is to bring awareness about this disease to the medical profession so that a cure can be. Porokeratosis 8 (disseminiert, aktinisch, superfiziell), mit Mutationen im SLC17A9-Gen im Chromosom 20 am Genort q13.33 Die Typen 3-8 können zusammengefasst als Porokeratose, aktinische disseminierte superfizielle bezeichnet werden Porokeratosis is a clonal disorder of keratinization characterized by one or more atrophic patches surrounded by a clinically and histologically distinctive hyperkeratotic ridgelike border called the cornoid lamella. Multiple clinical variants of porokeratosis are recognized

A complete organized library of all my videos, digital slides, pics, & sample pathology reports is available here: https://kikoxp.com/posts/5084 (dermpath) &.. Porokeratosis is a group of disorders involving Keratinization (cells beneath the skin turn into hair, nails, and skin). It is a rare, inherited condition that shows up as patches on the skin. In some cases, the condition can transform into cancer. Most of the time, clinical monitoring for potential cancer transformation is the only management. Porokeratosis is a rare skin disorder characterized by one or more annular plaques with a surrounding raised horny border that spreads centrifugally. Variants of porokeratosis have been described that differ in morphologic shapes, distribution, and clinical course (Schamroth et al., 1997). However, as noted by Sybert (2010), several families with expression of more than one variant of.

Porokeratosis definition at Dictionary.com, a free online dictionary with pronunciation, synonyms and translation. Look it up now porokeratosis,2,15 supporting a simple pathogenesis model in which loss-of-function mutations in MVK, PMVK, MVD,andFDPSresult in cholesterol deficiency in porokeratosis-affected skin, directlyleading to the disease phenotype. However, as has been demonstrated in other inherited metabolic dis Porokeratosis van Mibelli kan ook al op de kinderleeftijd voorkomen.Verruceuze papeltjes, meestal aan de extremiteiten, die langzaam uitgroeien tot lichtrood-bruine annulaire plaques of gegyreerde laesies, onregelmatige vormen, met schilferende rand en hyperkeratotisch of atrofisch centrum Porokeratosis of Mibelli. PM is the second most common form of porokeratosis. 3 It usually develops in childhood or adolescence, although adult onset has been described; it is more common in male patients (M-F ratio, 2-3:1). 46 It presents as one or more annular plaques with an atrophic, or less frequently, hyperkeratotic center. It is.

Porokeratosis: Types, causes, treatments, and picture

Porokeratosis unites a group of diseases characterized by a violation of keratinization. Porokeratosis is a disease inherited by autosomal dominant. Several clinical variants of pokeratosis, differing in grouping, quantity and location of vysypnyh elements are described: Mibelli's porokeratosis, characterized by single elements Due to the varying presentations and causes of plantar keratosis, it is crucial to make an accurate diagnosis to facilitate effective treatment. These authors present a comprehensive guide to biomechanical and dermatological lesions as well as options for management Porokeratosis visar sig som välavgränsade utslag med svagt upphöjda kanter (bestående av cellulärt protein - keratin). Mitten kan vara fjällig eller förtunnad. De växer gradvis till mellan 3 och 10 mm, men grupper av utslag kan se större ut Porokeratosis plaques can become malignant, so this skin health issue should be addressed properly. The condition occurs most often in light-skinned adults in their thirties or forties and appears in at least 6 distinct sub-types. Home Remedies for Porokeratosis

Porokeratosis - Pictures, Types, Causes, Treatmen

  1. ence, structure in the foot, or virus. They look much like IPK's but they can occur anywhere on the bottom of the foot. There is a core with surrounding thickened skin. There is no black dot present as there is in plantar warts. Some doctors believe porokeratosis are related.
  2. Porokeratosis is an uncommon dermatologic disorder. It is a disorder of keratinization that presents with keratotic papules or annular plaques with an elevated border. [1] It has a distinct histologic hallmark of cornoid lamella, which is a column of tightly fitted parakeratotic cells in the upper epidermis
  3. A condition called Intractable Plantar Keratosis (IPK) or Porokeratosis (PK) is a deep callus directly under the ball of the foot. A PK is caused by a dropped metatarsal, which happens when the metatarsal head drops to a lower level than the surrounding metatarsals and protrudes from the bottom of the foot
  4. ated superficial actinic porokeratosis (DSAP) is an uncommon skin condition that leads to reddish brown scaly spots. The spots are mostly seem on the arms and legs, but sometimes will show up on other sun-damaged skin
  5. Porokeratosis of Mibelli is a chronic and slowly progressive skin lesion due to excessive keratinization. Porokeratoses (singular: porokeratosis) comprise a class of skin conditions of which porokeratosis of Mibelli is one of six distinct variants
  6. Medical definition of porokeratosis: any of several often inherited skin disorders that arecharacterized by the proliferation of atypical keratinocytes and is marked by the presence of usually circular atrophic skin lesions which are surrounded by a ridgelike horny border
  7. ated superficial actinic porokeratosis being the most common one. Skin lesions result from somatic second-hit mutations in MVK, MVD, or PMVK, resulting in decreased expression of the respective enzymes.1,2 Enzyme.

Porokeratosis is a disorder of keratinization characterized by hyperkeratotic papules or plaques surrounded by a distinct peripheral, thin, ridge-like scale that expands centrifugally. Several variants of porokeratosis have been described, and a wide overlap between variants exists, suggesting that they are close in relation. Clinical variants. Thomas C et al. (2003) Hypertrophic perianal porokeratosis in association with superficial actinic porokeratosis of the leg. Clin Exp Dermatol 28: 676-677; Torkamani N et al. (2015) Disseminated superficial actinic porokeratosis accentuated by spray tan. Int J Dermatol 54:e545-54

Porokeratosis represents a group of relatively uncommon hereditary or acquired skin disorders of unknown aetiology characterized by abnormal keratinization. 1 Some contributing factors for the development of porokeratosis are immunosuppression, ultraviolet radiation and viral infections. 1-3 Nine clinical variants of porokeratosis have been. Actinic keratoses vary in appearance. Signs and symptoms include: Rough, dry or scaly patch of skin, usually less than 1 inch (2.5 centimeters) in diameter. Flat to slightly raised patch or bump on the top layer of skin. In some cases, a hard, wartlike surface. Color variations, including pink, red or brown. Itching, burning, bleeding or crusting Porokeratosis is a general term for a few skin conditions that block sweat glands. As the glands clog, you develop ridge-like bumps. These lesions often appear similar to corns. Sometimes the bumps are quite small, but patches may get larger and create small, reddish splotches on the skin. The specific condition you have determines where on the.

408 21 章 皮膚の良性腫瘍 21 4.汗孔角化症 porokeratosis 四肢や体幹,顔面に散在する,辺縁がふちどり状に隆起した 円形かつ褐色の角化性病変. 自覚症状がなく慢性に進行.まれに有棘細胞癌などに移行. cornoidlamella(コルノイド・ラメラ)と呼ばれる不全角 Porokeratosis may occur syndromically with craniosynostosis and anal anomalies (CAP syndrome). [64] Porokeratotic adnexal osteal nevus is the name proposed to incorporate porokeratotic eccrine ostial and dermal duct nevus (PEODDN) and porokeratotic eccrine and hair follicle nevus (PEHFN). It is considered a congenital lesion, usually developing.

The Mental Toll of Disseminated Superficial Actinic Porokeratosis. Scot's disseminated superficial actinic porokeratosis began to heal. The DSAP was something that I never experienced before. I was ashamed to go into public. People that met me thought that is was a communicable disease. The spots covered entirely my legs and arms, such that. Porokeratosis là một nhóm các tình trạng da trong đó có hiện tượng sừng hóa bất thường . Các tổn thương da của bệnh này khô và teo, với một đường viền tăng sừng giống như sườn núi giới hạn rõ được gọi là cornoid lamella (nhìn rõ nhất trên dermoscopy) [1]

Porokeratosis of Mibelli DermNet N

There are multiple other types of porokeratosis, which affect different age groups or present in slightly different ways. What causes disseminated superficial actinic porokeratosis? DSAP is thought to be caused by a variety of factors. There is a genetic predisposition, but ultraviolet light exposure is thought to be the main cause.. Disseminated Superficial Actinic Porokeratosis (DSAP) is an inherited skin condition which causes dry and flaky patches to appear on the skin, mostly on the legs and arms, explains Dr. Adam Mamelak, a board certified Dermatologist at Sanova Dermatology.Lesions caused by this condition present as a spot about the size of a pencil eraser, but can increase to even double that size

Background Porokeratosis (PK) is a rare skin disease of unknown etiology. It consists of a keratinization disorder, which may appear in several clinical forms and can undergo malignant transformation. The histopathological hallmark of PK is the cornoid lamella. While many topical, systemic, and surgical treatment modalities for PK have been described, no randomized controlled trials have been. A survey of the past 20 years of Japanese literature revealed 198 porokeratosis patients, 23 of whom developed squamous cell carcinomas, Bowen's disease (squamous cell carcinoma in situ), and/or basal cell carcinomas on the porokeratosis skin lesions (11.6%). Malignant transformation was not found in the 55 patients of actinic-type porokeratosis Porokeratosis is a rare disorder characterized by atrophic macules or patches, with a well‐defined ridge‐like hyperkeratotic border called cornoid lamella. Although the exact pathogenesis is unknown, drug associated cases have recently been reported in the literature. As such, we systematically reviewed and identified drugs associated with. The Asia Pacific porokeratosis treatment market is segmented into Japan, China, India, the Republic of Korea, Australia, and the Rest of Asia Pacific. The Middle Eastern and African porokeratosis treatment market is segmented into the Middle East and Africa. Regional Market Summary. Global Porokeratosis Treatment Market Share, by Region, 2017 (%

Porokeratosis - Treatment, Pictures, Symptoms and Cause

Porokeratose (Porokeratosis) - Symptome, Ursachen und

To the Editor: There exist several case reports documenting a rare, atypical variant of porokeratosis that evolves rapidly and may affect the entire body. Several descriptive terms have been proposed attempting to characterize this variant, including inflammatory disseminated superficial porokeratosis (DSP), eruptive pruritic papular porokeratosis, and eruptive disseminated porokeratosis (EDP. Important discovery made at Anhui Medical University in China. NEWS STORY - Sept 16, 2012 - A team of researchers at Anhui Medical University in China and BGI has found strong evidence that there is a link between mutations of the mevalonate kinase gene (MVK) and DSAP. It is a major step toward discovering the genetic mechanism that causes DSAP, and sheds light on its further molecular. I have had porokeratosis since 2010. I have seen a dermatologist for years--using mostly steroid creams and phototherapy. What is finally working for me and amazingly fast is Capzasin gel with menthol. It helps the itch and heals the lesions. I bought it because I also have prurigo nodularis and it is working on that as well

POROKERATOSIS PLANTARIS- Diagnosis, Symptoms, Treatment

Wikipedia is a free online encyclopedia, created and edited by volunteers around the world and hosted by the Wikimedia Foundation I just started getting serious about finding more answers and help for the porokeratosis- the itching is driving me crazy.. Reply. June 25, 2016 at 11:04 am . catherine macarthur. Hi DSAP institute - thank you for all your amazingly prepared information. I have been diagnosed with DSAP for 12 months, and it is getting worse, and incredibly.

Definition of porokeratosis in the Definitions.net dictionary. Meaning of porokeratosis. What does porokeratosis mean? Information and translations of porokeratosis in the most comprehensive dictionary definitions resource on the web Genitogluteal porokeratosis: a clinical review Rajiv Joshi,1 Khushboo Minni2 1Department of Dermatology, P. D. Hinduja Hospital, Mumbai, India; 2Department of Dermatology, Mumbai Port Trust Hospital, Mumbai, India Abstract: Porokeratosis is an uncommon disorder of keratinization that presents with keratotic papules or annular plaques that expand centrifugally with a thread-like elevated border

Porokeratosis - PubMe

Porokeratosis plantaris discreta is a skin condition that occurs in adults, with a 4:1 female preponderance, characterized by a sharply marginated, rubbery, wide-based papules. It is also known as Steinberg's lesion. It was characterized in 1970. Plaque-type porokeratosis (also known as Classic porokeratosis and Porokeratosis of Mibelli. Porokeratosis is a clonal disorder of epidermal keratinization, which is characterized by hyperkeratotic papules or plaques that are surrounded by a thread-like elevated border [1, 2, 3]. The histopathologic hallmark of porokeratosis is the cornoid lamella, which is a thin column of parakeratosis that overlies a thin or absent granular layer. Porokeratosis (PK) is a rare group of keratinization disorders first described by Vittorio Mibelli in 1889, presenting as annular lesions with an atrophic center and a keratotic ridge .Common subtypes of PK include porokeratosis of Mibelli (PM), disseminated superficial actinic porokeratosis (DSAP), PK palmaris, plantaris, et disseminata (PPPD), punctate PK, and linear PK Porokeratosis ptychotropica is a rare form of porokeratosis first described by Lucker et al in 1995. 1 The entity is characterized by symmetrical red-brown verrucous plaques localized to the perianal cleft and extending to the buttocks, usually forming a butterfly-shaped appearance. The lesions tend to coalesce and expand centrally, with formation of small satellite lesions at the periphery. Treatment. Several treatment strategies have been tried for porokeratosis with varying response. The use of sunscreens and regular observation for malignant transformation is prudent. Other.

Porokeratosis: Causes, Treatment, and More

Keratosis pilaris is a common, harmless skin condition that causes small, hard bumps that may make your skin feel like sandpaper. You may have heard it called chicken skin. The bumps are. DSAP is one of the six variants of porokeratosis, including linear porokeratosis, porokeratosis of Mibelli, punctate porokeratosis, porokeratosis palmaris et plantaris disseminata, and nonactinic disseminated superficial porokeratosis. 2 DSAP lesions are distinguished by their late onset and prevalence in sun-exposed areas while sparing the. Disseminated Superficial Actinic Porokeratosis (DSAP) is the most common subtype of porokeratosis, an uncommon skin condition that results in the manifestation of small patches of lesions of varying sizes on skin; Disseminated Superficial Actinic Porokeratosis is generally seen during young to middle adulthood The present study was performed in order to define the clinical manifestations of porokeratosis, with particular emphasis on genital porokeratosis. A total of 55 cases of porokeratosis were retrospectively reviewed between 2000 and 2007 from Huashan Hospital (Shanghai, China). Out of 55 cases, there were 22 cases of porokeratosis of Mibelli, 17 cases of disseminated superficial actinic. Porokeratosis are not associated with any particular type bony prominence, structural problem in the foot, or virus. They look much like IPK's but they can occur anywhere on the bottom of the foot. There is a deep core with thickened skin surrounding the core, and no black dot present as there is in plantar warts

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Multiple MDP is a rare type of porokeratosis, which has been reported as a late-onset skin reaction after irradiation, and was first described in 2001 by Pujol et al. Although the pathognomonic finding of MDP is a typical feature of acornoid lamella, it should be clinically differentiated from other digitate keratoses or other radiation-induced skin reactions The link between classic porokeratosis and the development of squamous cell proliferations is well established. Ninomiya et al 3 noted a possible mechanism of p53 overexpression in the epidermis of porokeratotic lesions that may make the lesions particularly susceptible to the development of immunosuppression-induced SCC. Etanercept is an immune-modulating drug with well-known. Fluorouracil may cause redness, soreness, scaling, and peeling of affected skin after 1 or 2 weeks of use. This effect may last for several weeks after you stop using the medicine and is to be expected. Sometimes a pink, smooth area is left when the skin treated with this medicine heals. This area will usually fade after 1 to 2 months A) Porokeratosis is characterized by benign lesions, and it sometimes mimics Bowen's disease/squamous cell carcinoma in situ. Some cases of squamous cell carcinoma that were believed to have arisen from porokeratosis may have been squamous cell carcinoma in situ all along

Linear Porokeratosis | Dermatology | JAMA Dermatology

Porokeratosis: Causes, Symptoms, and Treatment

Porokeratosis in immunosuppressed and nonimmunosuppressed patients. Raychaudhuri SP, Smoller BR. Department of Dermatology and Pathology, Stanford University School of Medicine, California. Int J Dermatol 1992 Nov;31(11):781-2 Abstract quote. Porokeratosis is an uncommon, inherited, autosomally dominant disorder.. Porokeratosis. The ICD-10-CM Alphabetical Index is designed to allow medical coders to look up various medical terms and connect them with the appropriate ICD codes. There are 0 terms under the parent term 'Porokeratosis' in the ICD-10-CM Alphabetical Index Porokeratosis is a rare skin disease that affects less than 200,000 americans. the distribution of actinic porokeratosis (dsap) is the most common type of porokeratosis. the reported prevalence of.

Treatment of Porokeratosis of Mibelli With Combined Use of

Porokeratosis: Background, Pathophysiology, Etiolog

Clinical signs. onset at any age, more often in men, chronic course. the extremities, trunk, face. slightly atrophic lesion with hyperkeratotic border. patches with irregular borders, several cm in diameter (Mibelli type) disseminated small lesions, sometimes linear. increased risk of the squamous cell carcinoma cornoid lamella: a narrow vertical column of parakeratosis in the epidermal stratum corneum; characteristic of porokeratosis

Porokeratosis - PCD

porokeratosis (uncountable) (pathology) A disorder of keratinization that is characterized by the presence of a cornoid lamella, a thin column of closely stacked, parakeratotic cells extending through the stratum corneum with a thin or absent granular layer. Synonyms. keratoatrophoderma; Further reading. porokeratosis on Wikipedia. Wikipedi Porokeratosis is a heterogenous group of disorders of disordered keratinization whose exact pathogenesis is unknown. There are five variants recognized: classic porokeratosis of Mibelli. Definition: Porokeratosis is a specific disorder of keratinization that is characterized histologically by the presence of a cornoid lamella, a thin column of closely stacked, parakeratotic cells extending through the stratum corneum with a thin or absent granular layer.. Images. Prominent hypekeratosis with well-developed cornoid lamellae in porokeratosis of Mibell Porokeratosis represents a group of disorders of epidermal keratinization which are characterized by the histopathological feature of the cornoid lamella, a column of tightly fitted parakeratotic cells. The aetiology of porokeratosis is still unclear Porokeratosis is a disorder of keratinization traditionally classified into 5 main variants based on clinical appearance: porokeratosis of Mibelli, disseminated superficial actinic porokeratosis (DSAP), disseminated superficial porokeratosis (DSP), porokeratosis palmaris et plantaris disseminata, and linear porokeratosis (LP). 1 Other rarer.

lichen planus - Humpath

Disseminated superficial actinic porokeratosis (DSAP) is a chronic condition characterized by numerous atrophic papules and patches with a distinctive peripheral keratotic ridge, typically found on sun-exposed areas. 1,2 Treatment of DSAP is warranted not only for cosmetic and symptomatic benefits but also to prevent malignant transformation. 3,4 Successful treatment of DSAP often is difficult. Porokeratosis (PK) is a term encompassing a group of uncommon diseases of keratinization, presenting with varying clinical aspects but sharing a common histopathological aspect, i.e. the presence of the cornoid lamella Porokeratosis are dry patches on the arms or legs which are characterised by the ridge-like border that surrounds them. There are different types of Porokeratosis with the most common type being DSAP ('Disseminated Superficial Actinic Porokeratosis') porokeratosis (uncountable) A disorder of keratinization that is characterized by the presence of a cornoid lamella, a thin column of closely stacked, parakeratotic cells extending through the stratum corneum with a thin or absent granular layer. Synonyms . keratoatrophoderma; Further reading . porokeratosis on Wikipedia. Wikipedi